Flowers for Algernon
This book is often given to high school students, but stands up well as an adult read. I think the best part about it is what Charlie does once he starts being intelligent; he suddenly likes art and making things and scientific theory. I think the altruism and openness of that time shows that the experiment, such as it was, didn't change everything. It's fun to think about. Also, this book made me cry the first time I read it. I was 25. - @RichardLitt
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